In capillary electrophoresis, the choice of detection method can significantly impact the sensitivity of your analysis. After separating DNA, RNA, or proteins by size and charge, detecting these molecules with precision is crucial for accurate results. Different detection methods—such as UV absorption, fluorescence, and conductivity—offer varying levels of sensitivity, but how do they compare?

Each detection method has unique strengths, with fluorescence detection often hailed as the gold standard for its superior sensitivity. But what exactly makes fluorescence detection so powerful in capillary electrophoresis? And when might other methods, like UV absorption or conductivity detection, be the right choice?

Grab the explanation and let's ace those experiments together!